Diethyl ethoxymethylene malonate is an important organic compound often used as an intermediate in drug synthesis, especially in the manufacture of drugs such as norfloxacin, chloroquine, and romefloxacin. It is a colorless, transparent, viscous liquid, prepared by the condensation of diethyl malonate and triethyl orthoformate to remove ethanol. It is a key raw material in the pharmaceutical and pesticide industries.
| Chemical Name | Diethyl Ethoxymethylene Malonate |
| Chemical Formula | C10H16O5 |
| CAS Number | 87-13-8 |
| Appearance | Colorless Liquid |
| Melting Point | -33℃ |
| Boiling Point | 279-281℃ |
| Density (×20), g/cm³ | 1.080 g/mL at 20℃ |
| Molecular weight | 216.23 |
| Refractive index (n₅D) | Insoluble in water |
An important organic raw material containing multiple active groups in its molecule, capable of undergoing condensation polymerization and cyclization condensation with various substances. It is widely used in the synthesis of pharmaceuticals, pesticides, and adjuvants, and is an intermediate in the production of chloroquine, norfloxacin, and romefloxacin.
This product is packaged in plastic drums or double-layered drums with plastic inner linings. During transportation, care should be taken to prevent violent shaking, and to protect it from moisture, rain, and direct sunlight. This product should be stored in a dry, cool warehouse and should not be stored in the open air. Keep away from heat sources and open flames, and store in a cool place.
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